Having a wound in your mouth can be very uncomfortable, and in some cases, can lead to serious health issues. Developing a wound in your mouth can happen due to a number of factors, and regardless of the reason, it’s something that needs to be taken seriously.
Failing to properly care for a mouth wound can lead to infections in some cases, and at the very least, it will make the problem last longer if it goes untreated.
Researchers in Thailand recently examined the ability of cannabidiol (CBD) to treat oral inflammation, gingival wounds, and ulcers by using a scratch test assay and evaluating cytotoxicity.
“The hemp extract and CBD significantly decreased TNF-α release by up to 91.05 ± 2.91% and 50.78 ± 7.21% of LPS activity, respectively, in a dose-dependent manner, compared to 10 µg/mL hydrocortisone (61.67 ± 3.79%). The hemp extract and CBD also significantly decreased IL-1β release, also in dose-dependent response, up to 78.03 ± 3.34% and 85.87 ± 1.11% of LPS activity, respectively, compared to 5 µg/mL hydrocortisone (80.81 ± 3.55%).” the researchers stated.
“The mean percentage of closure of the wound area was 27.92 ± 1.21% when exposed to 5 µg/mL hemp extract and 33.49 ± 1.67% when exposed to 0.5 µg/mL CBD, compared to 24.34 ± 2.29% for non-treated control.” the researchers went on to say.
“Our study demonstrates that both hemp extract and CBD can inhibit TNF-α and IL-1β production in LPS-induced RAW 264.7 cells and promote wound healing in HGF-1 cells. This is the first to show that short-term exposure to hemp extract and CBD promoted gingival fibroblast wound healing, demonstrating that hemp extract and CBD have potential benefits in the treatment of oral inflammation and ulcers.” the researchers concluded.
If you are experiencing any of the conditions mentioned in this article make sure to contact a medical professional as soon as possible before trying any new treatments.